Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
49908 | Catalysis Communications | 2015 | 4 Pages |
Abstract
•An efficient, green and scale-up synthesis of amides has been developed.•Amides are readily obtained from esters and amines.•Ru-MACHO is used as a readily available catalyst.•Amides are prepared in moderate to excellent yields and on multi-gram scale.
An efficient, green and scale-up synthesis of amides from esters and amines has been developed using Ru-MACHO as a readily available catalyst. A diverse range of amides were obtained in moderate to excellent yields (55–98%). Furthermore, when the scale of the amidation reaction was increased to 240.0 mmol, the desired amide still could be obtained in high yield (48.2 g of N-benzylbenzamide, 95%).
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Qian Han, Xingquan Xiong, Sizhong Li,