Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5020441 | Journal of the Mechanical Behavior of Biomedical Materials | 2017 | 16 Pages |
Abstract
Health problems related to the stomach are among the most important sources of morbidity in industrialized countries. There is evidence that mechanics may play an important role in various such pathologies. However, so far experimental data characterizing the mechanical properties of gastric tissue remain scarce, which significantly limits our understanding of the mechanics of the stomach. To help close this gap, we performed biaxial mechanical tests of porcine gastric tissue patches. Our experiments reveal a considerable anisotropy and different mechanical properties in the three major regions of the stomach (fundus, corpus, antrum). Moreover, they demonstrate that the mechanical properties of the gastric wall and the physiological function of the different regions of the stomach are closely related. This finding suggests that further examination of the mechanics of the gastric wall may indeed be a promising avenue of research towards a better understanding of the organic causes of frequent health problems related to the stomach.
Related Topics
Physical Sciences and Engineering
Engineering
Biomedical Engineering
Authors
R.C. Aydin, S. Brandstaeter, F.A. Braeu, M. Steigenberger, R.P. Marcus, K. Nikolaou, M. Notohamiprodjo, C.J. Cyron,