| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 50248 | Catalysis Communications | 2014 | 4 Pages |
Abstract
•Efficient modified Skraup reaction and Bamberger rearrangement•Modified Skraup reaction without As2O5•Synthesis of 6-hydroxyquinoline under microwave irradiation conditions•Synthesis of 6-hydroxyquinoline via a domino reaction
An efficient and modified Skraup reaction and Bamberger rearrangement in neat water were developed using nitrobenzene and an inexpensive, abundant and environmentally-friendly glycerol under microwave irradiation conditions was furnish regioselectively to the 6-hydroxyquinoline. The target compound was obtained in 77% yield via efficient domino reaction with a “one pot eleven steps”.
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Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Hanen Saggadi, Denis Luart, Nicolas Thiebault, Isabelle Polaert, Lionel Estel, Christophe Len,