Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5030824 | Biosensors and Bioelectronics | 2018 | 27 Pages |
Abstract
Polydopamine (PDA) can be formed by monomeric self-polymerization in water. This convenient behavior was exploited to prepare a molecularly imprinted polymer (MIP) layer on the surface of multi-walled carbon nanotubes (MWCNTs) with sunset yellow (SY) as a template molecule. The prepared nanocomposites were characterized, and their electrochemical behavior towards SY was investigated. Under the optimized conditions, a glassy carbon electrode modified with the imprinted nanocomposite showed a highly selective and ultrasensitive electrochemical response to SY compared with the performance of control electrodes and previously reported electrochemical sensors for SY. The improved behavior of the developed sensor can be attributed to its superficial highly matched imprinted cavities on the excellent electrocatalytic matrix of MWCNTs and the electronic barrier of the non-imprinted PDA to outside molecules. The fabricated sensor expressed a linear relationship to SY concentrations from 2.2 nM to 4.64 μM with a detection limit of 1.4 nM (S/N = 3). The sensor also exhibited excellent selectivity for SY over its structural analogs, good stability, and adequate reproducibility. The prepared sensor was successfully used to detect SY in real spiked samples. This methodology has potential application value and may be readily adapted to design other PDA-based MIP sensors.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Zheng-Zhi Yin, Shu-Wen Cheng, Li-Bin Xu, Hong-Ying Liu, Kai Huang, Lei Li, Yun-Yun Zhai, Yan-Bo Zeng, Hai-Qing Liu, Yong Shao, Zu-Lei Zhang, Yi-Xia Lu,