Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5031571 | Biosensors and Bioelectronics | 2017 | 20 Pages |
Abstract
In this study, we designed and fabricated an electrochemical impedance aptasensor based on Au nanoparticles (Au-NPs) coated boron-doped diamond (BDD) modified with aptamers, and 6-mercapto-1-hexanol (MCH) for the detection of bisphenol A (BPA). The constructed BPA aptasensor exhibits good linearity from 1.0Ã10-14 to 1.0Ã10â9 mol Lâ1. The detection limitation of 7.2Ã10-15 mol Lâ1 was achieved, which can be attributed to the synergistic effect of combining BDD with Au-NPs, aptamers, and MCH. The examine results of BPA traces in Tris-HCl buffer and in milk, UV spectra of aptamer/BPA and interference test revealed that the novel aptasensors are of high sensitivity, specificity, stability and repeatability, which could be promising in practical applications.
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Authors
Yibo Ma, Junsong Liu, Hongdong Li,