Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5031677 | Biosensors and Bioelectronics | 2017 | 41 Pages |
Abstract
Graphene's success has stimulated great interest and research in the synthesis and characterization of graphene-like 2D materials, single and few-atom-thick layers of van der Waals materials, which show fascinating and technologically useful properties. This review presents an overview of recent electrochemical sensors and biosensors based on graphene and on graphene-like 2D materials for biomarkers detection. Initially, we will outline different electrochemical sensors and biosensors based on chemically derived graphene, including graphene oxide and reduced graphene oxide, properly functionalized for improved performances and we will discuss the various strategies to prepare graphene modified electrodes. Successively, we present electrochemical sensors and biosensors based on graphene-like 2D materials, such as boron nitride (BN), graphite-carbon nitride (g-C3N4), transition metal dichalcogenides (TMDs), transition metal oxides and graphane, outlining how the new modified 2D nanomaterials will improve the electrochemical performances. Finally, we will compare the results obtained with different sensors and biosensors for the detection of important biomarkers such as glucose, hydrogen peroxide and cancer biomarkers and highlight the advantages and disadvantages of the use of graphene and graphene-like 2D materials in different sensing platforms.
Keywords
AFMDMFPBSIL-6SDSIgGRSDEDCCNTSDPVCPEEDXPolypyrroleDETSCEg-C3N4PPyPSAIgEflavin adenine dinucleotideLSVPdNPsHRPPTZGDHGCEGSPEBNSGRENHSTMBSWVTMDsN-hydroxysuccinimideAuNCsPDDA2D nanomaterialsGold nanocubes1-ethyl-3-(3-dimethylaminopropyl)carbodiimide3-aminopropyltriethoxysilaneAgNPsAuNPsBSACeATransition metal dichalcogenidesMNPsPANINPsrGOα-fetoproteinAscorbic acidbovine serum albuminGlucose oxidaseUric acidCarbon paste electrodeglassy carbon electrodeGraphene electrodeSaturated Calomel Electrodedirect electron transferrelative standard deviationhuman interleukin-6HCGIndium tin oxideGraphene oxideReduced graphene oxidetitanium isopropoxide IgE, immunoglobulin Eimmunoglobulin GITOTemFADGoxElectrochemical biosensorsEISAFPELISAEnzyme-linked immunosorbent assayLOD یا Limit of detectionHADDopaminedimethylformamidesodium dodecyl sulfateelectrochemical sensorsphosphate buffer salinePhenothiazinelower limit of detectionSEMAPTESTransmission electron microscopyatomic force microscopyNADHNanoparticlesGold nanoparticlesSilver nanoparticlesPalladium nanoparticlesGraphene nanosheetsboron nitride nanosheetsCarbon nanotubesBiomarkersboron nitridecarbon nitrideNAD, nicotinamide adenine dinucleotideHemoglobinHCG, Human chorionic gonadotropinDifferential pulse voltammetryCyclic voltammetrySquare Wave VoltammetryLinear sweep voltammetryAntibodyprostate-specific antigenPAMAMHorseradish peroxidasepolyamidoamine dendrimerPolyanilineChitGlassy carbonChitosanGrapheneGlucose dehydrogenase
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Paolo Bollella, Giovanni Fusco, Cristina Tortolini, Gabriella Sanzò, Gabriele Favero, Lo Gorton, Riccarda Antiochia,