Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5040584 | Brain, Behavior, and Immunity | 2017 | 4 Pages |
Abstract
Toxoplasma gondii infection reduces aversion to cat odors in male rats. Relevant proximate mechanisms include interaction of gonadal testosterone and brain nonapeptide arginine-vasopressin. Both of these substrates are sexually dimorphic with preferential expression in males; suggesting either absence of behavioral change in females or mediation by analogous neuroendocrine substrates. Here we demonstrate that Toxoplasma gondii infection reduces aversion to cat odor in female rats. This change is not accompanied by altered steroid hormones; cannot be rescued by gonadal removal; and, does not depend on arginine-vasopressin. Thus behavioral change in males and female occur through non-analogous mechanisms that remain hitherto unknown.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Samira Abdulai-Saiku, Ajai Vyas,