Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5123081 | Public Health | 2016 | 7 Pages |
â¢Examine the impact of the measures, the use and cost of antipsychotics.â¢Drug utilization study, data were obtained from the CONCYLIA database and presented as DID and DTC.â¢Typical antipsychotics prescriptions decreased; atypical increased. Global cost of antipsychotics only began to fall after measures to low medicines prices.â¢Several health policy measures eventually failed to avoid the increase in antipsychotics use.
ObjectivesAntipsychotics are currently used to treat different diseases; even some off-labelled conditions are treated with this medication. Consumption and cost of antipsychotic drugs sharply increased in Spain after second-generation drugs were marketed; several regulatory measures were adopted to curb this trend. The aim of this study was to examine the impact of these measures upon the use and cost of antipsychotics.Study designStudy of drug use (SDU) from 1995 to 2012. Consumption and cost data were obtained from the CONCYLIA database; this database contains the retail community pharmacies sales of medicinal products reimbursed by the National Health System in Castilla y León (Spain).MethodsData are presented as defined daily doses per 1000 inhabitants per day (DID) and day treatment cost (DTC).ResultsFirst-generation antipsychotics prescriptions gradually decreased from 3.0 to 1.8 DID; meanwhile, prescriptions for second-generation antipsychotics considerably increased from 0.3 to 9.9 DID. The use of risperidone dropped after the marketing of its structural derivative paliperidone with a similar efficacy but with a substantially higher cost per day. In 2011 and thereafter, patients in Spain began to pay a part of the medications cost, but this did not decrease antipsychotics consumption. Global cost of antipsychotics only began to fall after measures were adopted to lower the price of medicines because of the economic collapse in Spain after May 2010.ConclusionSeveral health policy measures have tried to reduce antipsychotics consumption in Spain, special ways of dispensing, marketing of generic drugs and special economic measures for patients. These measures eventually failed to avoid the increase in antipsychotics use. The cost only dropped when lowering prescription drug prices took place.