Computing the variance of a conditional expectation via non-nested Monte Carlo

Computing the variance of a conditional expectation has often been of importance in uncertainty quantification. Sun et al. has introduced an unbiased nested Monte Carlo estimator, which they call 112-level simulation since the optimal inner-level sample size is bounded as the computational budget increases. In this letter, we construct unbiased non-nested Monte Carlo estimators based on the so-called pick-freeze scheme due to Sobol'. An extension of our approach to compute higher order moments of a conditional expectation is also discussed.