Article ID Journal Published Year Pages File Type
5132308 Chemometrics and Intelligent Laboratory Systems 2017 9 Pages PDF
Abstract

•Responses model uncertainty impact on Pareto frontier is investigated.•Suboptimal solutions choice and unexpected results in practice can be avoided.•Reproducibility of optimal solutions in productive environment is assessed.•Usefulness of metrics to assess solutions reproducibility is illustrated.

Natural process variability and model's uncertainty impact on nondominated solutions reproducibility cannot be ignored to assure that product or process will perform as expected when theoretical results are implemented in productive environments. To help the decision-maker in making more informed decisions when he/she selects a nondominated solution, two metrics are used to assess the predicted variability of nondominated solutions; one of them (the predicted standard error) quantifies the uncertainty in the estimated value for each response, the another one (the quality of predictions) quantifies the uncertainty associated to each generated solution. Supplementary material is provided to help the practitioners in calculating the metric values.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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