| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5134633 | Journal of Analytical and Applied Pyrolysis | 2017 | 8 Pages |
â¢Pyrolysis of ethyl 2-amino-5-arylazo-6-phenylnicotinates gave 2-amino, 2,5-diamino and 5-arylazopyridine derivatives.â¢Pyrolysis of 5-arylazonicotinonitriles gave 5-aminonicotinonitriles and pyrido[3,4-c]cinnoline-1-carbonitriles.â¢The obtained pyridine derivatives are of potential utility in pharmaceutical and dye industry.
FVP and static pyrolysis of ethyl 2-amino-5-arylazo-6-phenylnicotinates 7a-d and 5-arylazonicotinonitriles 8a-c enabled the synthesis of the hitherto unreported pyridine derivatives of potential utility in pharmaceutical and dye industry including 5-arylazopyridine-2-amines, 6-arylpyridine-2,5-diamines, 5-aminonicotinonitriles and pyrido[3,4-c]cinnolines.
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![Gas-phase pyrolysis of arylazonicotinates and nicotinonitriles: Routes towards new aminopyridine and pyrido[3,4-c]cinnoline derivatives](/preview/png/5134633.png "First Page Preview: Gas-phase pyrolysis of arylazonicotinates and nicotinonitriles: Routes towards new aminopyridine and pyrido[3,4-c]cinnoline derivatives")