| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5137940 | Journal of Pharmaceutical and Biomedical Analysis | 2017 | 32 Pages |
Abstract
Bioavailability of each anthocyanin was then estimated by comparing the relative content in plasma vs extract. The 15 anthocyanins behaved differently in term of bioavailability and both the aglycone and the sugar moiety were found to affect the absorption. For instance, arabinoside moiety was detrimental while cyanidin enhanced bioavailability. Computational studies permitted to rationalize such results, highlighting the role of glucose transporters (sGLT1 and GLUT2) in anthocyanins absorption. In particular a significant correlation was found for the 15 anthocyanins between sGLT1 and GLUT2 recognition and absorption.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
G. Baron, A. Altomare, L. Regazzoni, V. Redaelli, S. Grandi, A. Riva, P. Morazzoni, A. Mazzolari, M. Carini, G. Vistoli, G. Aldini,