Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5138744 | Journal of Trace Elements in Medicine and Biology | 2017 | 17 Pages |
Abstract
After the washing procedure to minimize the external contamination, from each hair sample two aliquots were taken; the first was used for direct analysis of Hg by TDA-AAS and the second was digested for Hg determination by the ICP-MS. Results indicated that the two data sets were fully comparable (median; TDA-AAS, 475 ng gâ1; ICP-MS, 437 ng gâ1) and were not statistically different (Mann-Whitney test; p = 0.44). The two techniques presented results with a good coefficient of correlation (r = 0.94) despite different operative ranges and method limits. Both techniques satisfied internal performance requirements and the parameters for method validation resulting sensitive, precise and reliable. Finally, the use of the TDA-AAS can be considered instead of the ICP-MS in hair analysis in order to reduce sample manipulation with minor risk of contamination, less time consuming due to the absence of the digestion step and cheaper analyses.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Francesco Domanico, Giovanni Forte, Costanza Majorani, Oreste Senofonte, Francesco Petrucci, Vincenzo Pezzi, Alessandro Alimonti,