Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5138970 | Microchemical Journal | 2018 | 6 Pages |
Abstract
In conclusion, CYP2D6 genotyping for the most frequent allelic variants was able to reliably predict CYP2D6 phenotypes in most donors; however, the external factors modifying the phenotypic appearance of CYP2D6 had to be taken into account. Personalized medication strategy should include monitoring of CYP2D6 genotype in a more comprehensive manner and should take external factors into consideration for an appropriate prediction of CYP2D6 metabolizing capacity.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Ádám Ferenc Kiss, Katalin Tóth, Cintia Juhász, Manna Temesvári, József Paulik, Gábor Hirka, Katalin Monostory,