Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5140582 | Talanta | 2017 | 10 Pages |
Abstract
In this work, a novel Gemini-type sulfobetaine-based hybrid monolith was firstly fabricated by co-polymerization of a homemade Gemini-type sufobetaine, 1, 3 - bis (N - (3- sulfopropyl) - N - (methacrylic acid - 2 - hydroxy propyl ester) - N - methyl ammonium) - propane (BSMMP) with vinyltrimethoxysilane (VTMS) and tetramethoxysilane (TMOS) in present of 2â²-azobis (2-methylpropionamidine) dihydrochloride (V50) as initiator. It is demonstrated that the resulting monolith possess homogeneous pore structure and good mechanical strength, and shows excellent hydrophilicity and good separation performance for a variety of polar probe compounds, including nucleoside, bases, phenol, amide. Finally, the potential application of the resulting monolith in complex sample was successfully proved by separating a BSA digest in gradient elution mode.205
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Wangming Tan, Feng Chang, Yan Shu, Ye Chen, Jingjing Liu, Yingzhuang Chen, Ming Ma, Bo Chen,