Fluorescein applications as fluorescent probes for the detection of analytes

Fluorescein is an important class of fluorescent probes. This article reviewed fluorescein fluorescent probes in the past two years according to classification of different analytes including metal ions, anions, small molecules and biological macromolecules. The synthesis method, optical properties, possible mechanisms and applications of “OFF-ON” fluorescein fluorescent probes were summarized in here.128