Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5141546 | TrAC Trends in Analytical Chemistry | 2017 | 55 Pages |
Abstract
Antibiotic contamination and abuse are universal phenomena, accordingly antibiotic resistance has emerged as a serious issue globally in recent years. To detect antibiotics and their residues in the environment, foods, drugs and biological samples, numerous analytical techniques have been developed. Among them, aptamer-based methods are considered to be highly sensitive and selective and have been applied to the detection of various antibiotics in different samples. We present a systematical and critical review on the antibiotic-specific aptamers and their application in detection of antibiotics in different matrices, focusing on the recent advances in optical and electrochemical aptasensors, aptamer-affinity based sample purification, as well as the promising label-free and multiplex determination.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yi Yang, Shuo Yin, Yongxin Li, Dan Lu, Jing Zhang, Chengjun Sun,