Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5141578 | TrAC Trends in Analytical Chemistry | 2017 | 46 Pages |
Abstract
A total of 2572 differentially expressed proteins or peptides were pooled from 89 studies focused on 57 diseases. Data analysis highlighted inflammation as a biological process modulated by all diseases. However, specific inflammatory signatures are associated with specific diseases and/or aetiologies. Moreover, specific biological processes were identified for specific groups of pathologies and unique proteins identified. Overall, integrative data analysis from urine proteomics/peptidomics reinforces the clinical potential of this body fluid for the clinical management of distinct diseases.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Paulo André Dias Bastos, Antonia Vlahou, Adelino Leite-Moreira, Lúcio Lara Santos, Rita Ferreira, Rui Vitorino,