Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5141641 | TrAC Trends in Analytical Chemistry | 2017 | 17 Pages |
Abstract
Because of the low concentration levels in plasma, blood, urine, and other metabolites, adequate analytical methods should be used for quantification of drugs at the trace levels. Molecularly imprinted polymers (MIPs) are tailor made and stable polymers with special molecular recognition abilities that because of their high selectivity can be used for the extraction of selected target analytes and structurally related analogues in many bioanalytical approaches. Nowadays, MIPs are rapidly progressing for the analysis of drugs in biological, environmental, and pharmaceutical samples. In this review, we discuss the novel developments and uses of MIPs as new sorbents and fibers in solid phase extraction (SPE) and solid phase microextraction (SPME), ultrasonic-assisted SPE, sensitive sensors, magnetic separations or conjugating with carbon materials for trace and ultra-trace determination of drugs. We believe that our review will be of assistance to drug analysis and analytical methods with highly selective separations/detections.
Keywords
CelLOQWWTPDPVCNTMIPDVBMWCNTHPTLCASAMOFSPENSAIDNIPSBSETFADFCDLLMESITCOCMAAENRVPUIIPNDVMNPICPMSEGDMAAIBNμ-SPESLMMNZO-desmethylvenlafaxineUCNPODVMiNPSPMEMMIPDMSOGC/FIDGC–MSHF-LPMEHPLC/UVLC–MSMicroextraction by packed sorbentDispersive liquid–liquid microextractionUHPLC-MS/MSethylene glycol dimethacrylateElectromembrane extractionSolid-phase extractionMolecularly imprinted solid phase extractionMicro-solid phase extractionacetylsalicylic acidTrifluoroacetic acidSalicylic acidMethacrylic acidGold electrodeMagnetic glassy carbon electrodeEnrofloxacinmitsolid-phase microextractionTetracyclineEISDrug analysisfluorescence detectionWastewater treatment plantTulathromycinMolecular imprinting technologySurface imprinting techniqueLOD یا Limit of detectionBiosensorsvendivinylbenzeneDiclofenacDimethyl sulfoxideCephalosporinCelecoxibElectrochemical impedance spectroscopyliquid chromatography–mass spectrometryUltra-high performance liquid chromatography-tandem mass spectrometrygas chromatography–mass spectrometryinductively coupled plasma mass spectrometrySupported liquid membraneNon-steroidal anti-inflammatory drugFluoroquinoloneMetronidazolelimit of quantificationlimit of detectionStir-bar sorptive extractionMISPEMagnetic molecularly imprinted polymerHollow fiber liquid phase microextractionUpconversion nanoparticlesMagnetic nanoparticleMulti-walled carbon nanotubesCarbon nanotubesMEPsemeDifferential pulse voltammetryCyclic voltammetryVenlafaxinenon-imprinted polymerMolecularly imprinted polymerIon-imprinted polymersMetal organic frameworkHigh performance liquid chromatography with ultraviolet detectionhigh performance thin layer chromatographyCocaineGas Chromatography-Flame Ionization Detector
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Saeedeh Ansari, Majid Karimi,