Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5141664 | TrAC Trends in Analytical Chemistry | 2017 | 60 Pages |
Abstract
Immunoassay is an emerging technique that has been used in the fields of food and environmental analysis to monitor and control hazardous residues. Multianalyte immunoassays (MAIAs) are favored because they can simultaneously determine several targets in a single test. In this review, an overview of various formats for the MAIA is given. New trends on how to produce antibodies, how to improve antibody specificity and how to manipulate assay formats to obtain the desired multi-analysis schemes are summarized. Finally, the limitations and prospects of MAIAs are discussed.
Keywords
CoMSIAscFvCDRIC50PCBsHRPDeoxynivalenolMRLsMIPSCoMFACCDdifloxacinQDsDIFSARVHHZENFQsMultianalyte immunoassayMCNs2D-QSAR3D-QSARBSADNAOPsbovine serum albumindeoxyribonucleic acidTROPolychlorinated biphenylscomparative molecular similarity indices analysiscomparative molecular field analysisTrovafloxacinELISAEnzyme-linked immunosorbent assaySPRSurface plasmon resonanceMaximum Residue LimitsFoodCharge-Coupled DeviceDONZearalenoneSarafloxacinOrganophosphorus pesticidesSulfonamideFluoroquinolonessingle-chain variable fragmentEnvironmentalcomplementarity determining regionMolecularly imprinted polymersquantum dotshypoxanthine-aminopterin-thymidinepolymerase chain reactionPCRImmunoassayCross-reactivityAntibodyHorseradish peroxidaseHAT
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yong-Fang Li, Yuan-Ming Sun, Ross C. Beier, Hong-Tao Lei, Shirley Gee, Bruce D. Hammock, Hong Wang, Zhanhui Wang, Xiulan Sun, Yu-Dong Shen, Jin-Yi Yang, Zhen-Lin Xu,