Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5142061 | Arabian Journal of Chemistry | 2017 | 25 Pages |
Abstract
The solubility and solubility product of the two ion-associates clomipraminium tetraphenylborate (CLP-TPB) and silicotungstate ((CLP)4-ST) were determined using conductimetric and potentiometric measurements applying the standard addition method. The obtained values from both conductimetric measurements and standard addition method are close to each other. Thermodynamic parameters ÎG, ÎH and ÎS have been determined. Sodium tetraphenylborate has been used for the determination of CLP.Cl in model solution and pharmaceutical preparation by conductimetric titrations. The proposed method allowed the determination of CLP.Cl within the range of 0.17-35.15Â mg. The accuracy of the method is indicated by the excellent recovery 99.95-101.23%, and the precision is supported by the low relative standard deviation 0.50-1.21%. The ruggedness and robustness of the proposed method were also studied.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Yousry M. Issa, Sabrein H. Mohamed, Shaimaa Abdel-Hakeem Elfeky,