| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5142102 | Arabian Journal of Chemistry | 2017 | 17 Pages |
Abstract
Synthesis of commercially available benzimidazole involves condensation of o-phenylenediamine with formic acid. The most prominent benzimidazole compound in nature is N-riosyldimethylbenzimidazole, which serves as a axial ligand for cobalt in vitamin B12. The benzimidazole and its derivatives play a very important role as a therapeutic agent e.g. antiulcer and anthelmintic drugs. Apart from this the benzimidazole derivatives exhibit pharmacological activities such as antimicrobial, antiviral, anticancer, anti-inflammatory, analgesic, etc. The substituted benzimidazoles are summarized in this review to know about the chemistry as well as pharmacological activities.
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Physical Sciences and Engineering
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Chemistry (General)
Authors
Salahuddin Salahuddin, Mohammad Shaharyar, Avijit Mazumder,