Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives

2-Oxo-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-6-phenylpyridin-3-carbnitriles (2a-c) and its derivatives containing 1,2,4-triazole (4a-c), thiazolo[3,2-b][1,2,4]triazole (5a-c), hydrazide (6a-c), pyrazolones (7a-c) and (8a-c) were synthesized. Structures of all these previously unknown compounds were confirmed by their spectral studies and elemental analysis. The compounds were screened for their antioxidant and antimicrobial activities.