Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5142550 | Arabian Journal of Chemistry | 2016 | 6 Pages |
Abstract
Synthesis of α-aminophosphonates by a three-component condensation of an aldehyde, amines and dialkyl phosphites in the presence of a non-ionic surfactant Triton X-100 catalyst at 70 °C in aqueous medium is accomplished. The advantages are high yield, mild reaction conditions, simple work-up and eco-friendliness. All the newly-synthesized compounds (4a-j) exhibited moderate in vitro antibacterial and antifungal activities.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Nemallapudi Bakthavatchala Reddy, Chereddy Syama Sundar, Chinthaparthi Radha Rani, Kunda Uma Maheswara Rao, Sandip Kumar Nayak, Cirandur Suresh Reddy,