Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5142613 | Chemistry and Physics of Lipids | 2017 | 33 Pages |
Abstract
Oxysterols are oxidized products of cholesterol that play several roles in various pathophysiological processes, including the control of lipid metabolism, immunological processes, and cytotoxicity. Mesenchymal stem cells are multipotent cells with properties of self-renewal and the ability to differentiate into other cell types, including osteoblasts and adipocytes. Here, we review the literature regarding the effects of oxysterols on mesenchymal stem cell differentiation and the main signaling pathways involved in this process.
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Authors
Débora Levy, Thatiana Correa de Melo, Jorge L.M. Ruiz, Sérgio P. Bydlowski,