Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5151869 | Inorganica Chimica Acta | 2016 | 21 Pages |
Abstract
The bimetallic Fe(III) complex of 2,6-bis(1,4,7-triazacyclonon-1-ylmethyl)-4-methylphenol relaxes supercoiled pUC19 DNA into the nicked form at low micromolar concentration in the presence of an external reducing agent and exhibits significant cytotoxic effects against colon LoVo cancer cells with an IC50 value 2.5 times lower than that of cisplatin.64
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Authors
Thaylan Pinheiro Araujo, Valentina Gandin, Paul Kavanagh, Jeremy Phillip Braude, Luca Nodari, Diego Montagner, Andrea Erxleben,