| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5151872 | Inorganica Chimica Acta | 2016 | 6 Pages |
Abstract
A trans-chelating ligand based on two 2-ethynyl-pyridine arms attached to a benzene ring was incorporated into DNA single strands by means of solid phase phosphoramidite synthesis to provide a tetradentate N4 coordination environment for metal cations favoring a square-planar geometry inside the DNA double helix. The binding of Cu(II) cations was investigated and an increase in the DNA melting temperature was observed upon metal binding.87
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Fernanda A. Pereira, Guido H. Clever,