| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152322 | Journal of Inorganic Biochemistry | 2018 | 36 Pages |
Abstract
Substitution of N-benzyl for an N-propargyl residue in the anticancer prodrug 4-(N-benzyl-N-ferrocenylaminocarbonyloxymethyl)phenylboronic acid pinacol ester led to reduction of its lipophilicity, improvement of its water solubility, decrease of its propensity towards aggregation and dramatic increase of its ROS-generating properties without any negative effect on its anticancer activity.154
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Steffen Daum, Svetlana Babiy, Helen Konovalova, Walter Hofer, Alexander Shtemenko, Natalia Shtemenko, Christina Janko, Christoph Alexiou, Andriy Mokhir,