| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152334 | Journal of Inorganic Biochemistry | 2017 | 43 Pages |
Abstract
A dicarboxylato platinum(II) complexes based on 1,2,4-triazolo[1,5-a]pyrimidine were synthesized and characterized by various analytical tools. The complexes containing 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine were shown to have higher in vitro cytotoxicity in the cisplatin-resistant A2780cis and OVCAR-3 cells and different the action mechanism than the clinical anticancer drugs (cisplatin and carboplatin).138
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Kamil Hoffmann, Joanna WiÅniewska, Andrzej Wojtczak, Jerzy Sitkowski, Agnieszka Denslow, Joanna Wietrzyk, Mateusz Jakubowski, Iwona Åakomska,