Article ID Journal Published Year Pages File Type
5152354 Journal of Inorganic Biochemistry 2017 7 Pages PDF
Abstract
A metalloporphyrin frame and platinum(II)-based groups were combined to produce two new pentacationic metalloporphyrinates. Both of them exhibited high singlet oxygen quantum yields and remarkable photocytotoxicity with appreciable phototoxic indexes. With outstanding tumor accumulation, cisplatin-based gallium porphyrinate almost completely inhibited tumor growth in an in vivo photodynamic therapy assay.64
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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