| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152367 | Journal of Inorganic Biochemistry | 2017 | 37 Pages |
Abstract
Coordination of the fac-Re(CO)3 moiety to bioactive thiosemicarbazones HL led to fac-[Re(CO)3Br(HL)] compounds with high activities on bloodstream Trypanosoma cruzi and good selectivities towards the parasite. Complexes convert into [Re2(CO)6(L)2] in solution and inhibit parasite mitochondrial respiration, effect shown by decrease of oxygen consumption rate, without generating radical oxygen species.88
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Esteban RodrÃguez Arce, Ignacio Machado, Belén RodrÃguez, Michel Lapier, MarÃa Carolina Zúñiga, Juan Diego Maya, Claudio Olea Azar, LucÃa Otero, Dinorah Gambino,