| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152384 | Journal of Inorganic Biochemistry | 2017 | 29 Pages |
Abstract
Synopsys: Two newly synthesised oxidovanadium(IV) complexes are capable of inhibiting moderately the activity of dipeptidyl peptidase IV (DPP IV) in vitro. These are the first examples of vanadium complexes able to target DPP IV in vitro.106
Keywords
GLP-1BEOVPTP1BACENAcAcGIPhIAPPAMPKDPP-IVIC50DMEM50% inhibition concentrationAMP-activated protein kinaseDMSODulbecco's modified Eagle's mediumPPARsacetylacetonateElectron paramagnetic resonanceEPRdipeptidyl peptidase IVDimethyl sulfoxideSchiff base complexesEnzyme inhibitorsProtein tyrosine phosphatase 1Bhuman islet amyloid polypeptideglucagon-like peptide-1glucose-dependent insulinotropic peptideMolecular dockingperoxisome proliferator-activated receptor
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Ming-jin Xie, Ming-rong Zhu, Chun-Mei Lu, Yi Jin, Li-Hui Gao, Ling Li, Jie Zhou, Fan-fang Li, Qi Hua Zhao, Hong-Ke Liu, Peter J. Sadler, Carlos Sanchez-Cano,