| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152386 | Journal of Inorganic Biochemistry | 2017 | 11 Pages |
Abstract
Pt(IV) prodrug 2 highly accumulate in cancer cells than normal ones and activated by endogenous reducing molecules to release cisplatin and indomethacin simultaneously, exhibiting selective inhibition to cancer cell lines and sensitivity to cisplatin-resistant cancer cells. Moreover, this prodrug reduces the invasiveness of tumor cells and disrupts capillary-like tube formation.70
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Weiwei Hu, Lei Fang, Wuyang Hua, Shaohua Gou,