| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152424 | Journal of Inorganic Biochemistry | 2017 | 52 Pages |
Abstract
Six new Pt(II)-based complexes were synthesized and characterized. Cytotoxicity evaluation and cell death in vitro was performed in four cancer cell lines and VERO cells as control. In addition, experimental and theoretical DNA binding assays were achieved. Overall, induction of cell death by dependent and independent DNA-Pt(II) interactions were possible.263
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Alan R. Cabrera, Christian Espinosa-Bustos, Mario Faúndez, Jaime Meléndez, Pablo Jaque, Constantin G. Daniliuc, Adam Aguirre, Rene S. Rojas, Cristian O. Salas,