| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152427 | Journal of Inorganic Biochemistry | 2017 | 50 Pages |
Abstract
Novel diamineplatinum(IV) complexes featuring axial carboxylato and equatorial halido or dicarboxylato ligands were synthesized and characterized. The ligand sphere had a significant influence on the lipophilicity and rate of reduction. Most cytotoxic platinum(IV) complexes showed IC50 values in the low micromolar and even nanomolar range.136
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Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Doris Höfer, Hristo P. Varbanov, Michaela Hejl, Michael A. Jakupec, Alexander Roller, Markus Galanski, Bernhard K. Keppler,