Article ID Journal Published Year Pages File Type
5152430 Journal of Inorganic Biochemistry 2017 14 Pages PDF
Abstract
An antidiabetic drug which mimics amylin, pramlintide, forms stable complexes with Zn(II). The metal binds to the imidazole of His18 and the amine group of Lys1. The initially well-soluble Zn(II)-pramlintide complex forms fibrillar aggregates after a lag-time of 20 h.161
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Authors
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