| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152453 | Journal of Inorganic Biochemistry | 2017 | 50 Pages |
Abstract
Three ruthenium(II/III) complexes containing the nucleobase analog 5,6,7-trimethyl-1,2,4-triazolo[1,5-a]pyrimidine (tmtp): cis,fac-[RuCl2(dmso)3(tmtp)] (1), mer-[RuCl3(dmso)(H2O)(tmtp)]·2H2O (2) and fac,cis-[RuCl3(H2O)(tmtp)2] (3) were prepared and structurally characterized. In vitro studies show their potential to become a new generation of highly effective and non-toxic antiparasitic agents to fight the neglected Chagas disease and leishmaniasis.280
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Marzena Fandzloch, José Manuel Méndez Arriaga, Manuel Sánchez-Moreno, Andrzej Wojtczak, Julia Jezierska, Jerzy Sitkowski, Joanna WiÅniewska, Juan Manuel Salas, Iwona Åakomska,