| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152457 | Journal of Inorganic Biochemistry | 2017 | 9 Pages |
Abstract
Three biotinylated platinum(IV) complexes (1-3) were designed and synthesized for cancer targeting therapy, which could bind with the over-expressed biotin-specific receptors on the cancer cell surface, and then release the cytotoxic platinum(II) species at the tumor site by glutathione or ascorbic acid under biologically relevant condition.181
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Jian Zhao, Wuyang Hua, Gang Xu, Shaohua Gou,