| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152493 | Journal of Inorganic Biochemistry | 2017 | 35 Pages |
Abstract
Four μ2-Cl bridged dinuclear Zn(II)/Mn(II) complexes with isoquinoline derivatives were synthesized and exhibited high cytotoxicity against various tumor cells with certain selectivity to tumor and normal cells, which induced intrinsic pathways-dependent apoptosis in cancer cells by triggering DNA damage which was caused by the reactive oxygen species (ROS) overproduction.83
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Feng-Yang Wang, Qian-Yu Xi, Ke-Bin Huang, Xiao-Ming Tang, Zhen-Feng Chen, Yan-Cheng Liu, Hong Liang,