| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152523 | Journal of Inorganic Biochemistry | 2016 | 6 Pages |
Abstract
Enzymatic oxidation of 1 by the horseradish peroxidase/H2O2 mixture afforded a short-life species with high inhibitory activity towards cytosolic thioredoxin reductase in vitro (IC50 = 0.125 μM). This species was identified as the radical 1* in its two mesomeric forms by UV-Vis and EPR spectroscopy and ab-initio calculations.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Valeria Scalcon, Anna Citta, Alessandra Folda, Alberto Bindoli, Michèle Salmain, Ilaria Ciofini, Sébastien Blanchard, José de Jésús Cázares-Marinero, Yong Wang, Pascal Pigeon, Gérard Jaouen, Anne Vessières, Maria Pia Rigobello,