Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5152555 | Journal of Inorganic Biochemistry | 2016 | 12 Pages |
Abstract
The platinum agents phosphaplatin exhibit anti-cancer mechanisms that are different from those of the classical platinum drug cisplatin. The following work demonstrates that phosphaplatin can induce anti-angiogenesis in both in vitro and in vivo experiments. Phosphaplatin downregulates gene expression of growth factors/receptors and can bind to protein targets.159
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Lu Yang, Shadi Moghaddas, Homa Dezvareh, Louiza Belkacemi, Steven J. Bark, Rathindra N. Bose, Loi H. Do,