| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152565 | Journal of Inorganic Biochemistry | 2016 | 42 Pages |
Abstract
In this work, two Ru(II) polypyridine complexes containing guanidinium ligands were synthesized and characterized. Both complexes exhibited antitumor activity to five different human tumor cells. Additionally, the two complexes displayed higher phototoxicity to tumor cells and almost no influence on normal cells upon irradiation at 450Â nm.62
Keywords
ESI-MSH2DCF-DATRISCDK1RIPAMLCTdppzFBSPBS1,10-Phenanthroline2′,7′-dichlorofluorescein diacetate3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideCt-DNADMSOCalf thymus DNAMTTROSradio-immunoprecipitation assayElectrospray Ionization Mass SpectrometryMetal-to-ligand charge transferTris(hydroxymethyl)aminomethaneApoptosisDimethyl sulfoxidefetal bovine serumCytotoxicityPhototoxicityPhosphate buffered salinePhenRu(II) complexPropidium iodideGuanidiniumReactive oxygen species
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Wen-Xiu Chen, Xing-Dong Song, Shu-Fen He, Jing Sun, Jia-Xi Chen, Tie Wu, Zong-Wan Mao,