Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5152586 | Journal of Inorganic Biochemistry | 2017 | 8 Pages |
Abstract
The oligomerization process of bovine pancreatic ribonuclease in the presence of cisplatin, carboplatin and oxaliplatin is compared. X-ray structures of the monomeric protein adducts formed with the three drugs explain the different effects exerted by the three drugs on enzymatic activity and protein aggregation.59
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Delia Picone, Federica Donnarumma, Giarita Ferraro, Giovanni Gotte, Andrea Fagagnini, Giovanna Butera, Massimo Donadelli, Antonello Merlino,