| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152602 | Journal of Inorganic Biochemistry | 2017 | 39 Pages |
Abstract
Mechanisms underlying the anti-tumor effect of two [Ru(III)-bis(aminophenolate)] complexes are investigated. A novel fully quantitative approach to DNA-[complex] binding is applied and quantitatively validated with time-resolved fluorescence spectroscopy. These complexes induce different programmed cell death routes and exert a different effect on the cell cycle despite their structural resemblance.165
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Orsolya Dömötör, Rodrigo F.M. de Almeida, Leonor Côrte-Real, Cristina P. Matos, Fernanda Marques, António Matos, Carla Real, Tamás Kiss, Ãva Anna Enyedy, M. Helena Garcia, Ana Isabel Tomaz,