Article ID Journal Published Year Pages File Type
5152607 Journal of Inorganic Biochemistry 2017 48 Pages PDF
Abstract
Five new organotin(IV) complexes viz., [Me2SnL1] (1), [Me2SnL2]n (2), [Me2SnL3] (3), [Ph3SnL1H]n (4) and [Ph3SnL3H] (5) (where L1 = (2S)-2-((E)-((Z)-4-hydroxypent-3-en-2-ylidene)amino)-3-(1H-indol-3-yl)propanoate, L2 = (2S)-(E)-2-((2-hydroxybenzylidene)amino)-3-(1H-indol-3-yl)propanoate and L3 = (2S)-(E)-2-((1-(2-hydroxyphenyl)ethylidene)amino)-3-(1H-indol-3-yl)propanoate were synthesized and characterized. The crystal structures of 1-4 were determined. Designed [Ph3SnL1H]n4 demonstrated potent apoptotic activity in melanoma cells ex vivo.111
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Authors
, , , , , , , , , , ,