Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5152607 | Journal of Inorganic Biochemistry | 2017 | 48 Pages |
Abstract
Five new organotin(IV) complexes viz., [Me2SnL1] (1), [Me2SnL2]n (2), [Me2SnL3] (3), [Ph3SnL1H]n (4) and [Ph3SnL3H] (5) (where L1Â =Â (2S)-2-((E)-((Z)-4-hydroxypent-3-en-2-ylidene)amino)-3-(1H-indol-3-yl)propanoate, L2Â =Â (2S)-(E)-2-((2-hydroxybenzylidene)amino)-3-(1H-indol-3-yl)propanoate and L3Â =Â (2S)-(E)-2-((1-(2-hydroxyphenyl)ethylidene)amino)-3-(1H-indol-3-yl)propanoate were synthesized and characterized. The crystal structures of 1-4 were determined. Designed [Ph3SnL1H]n4 demonstrated potent apoptotic activity in melanoma cells ex vivo.111
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Tushar S. Basu Baul, Pelesakuo Kehie, Andrew Duthie, Nikhil Guchhait, Nune Raviprakash, Raveendra B. Mokhamatam, Sunil K. Manna, Nerina Armata, Michelangelo Scopelliti, Ruimin Wang, Ulli Englert,