| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5152654 | Journal of Inorganic Biochemistry | 2017 | 31 Pages |
Abstract
This work describes the inactivation of urease, a nickel-containing enzyme that affects both human health and agriculture, by one of its most efficient inhibitors: catechol (CAT). The high-resolution structure of the CAT-urease covalent complex as well as quantum-mechanical computations contributed to the development of a kinetic model of the reaction.320
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Luca Mazzei, Michele Cianci, Francesco Musiani, Gábor Lente, Marta Palombo, Stefano Ciurli,