Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5152655 | Journal of Inorganic Biochemistry | 2017 | 9 Pages |
Abstract
We investigated how metal ions and cosolutes stabilize particular topologies by analyses of oligodeoxynucleotides modified with 2â²-deoxyxanthosine and 8-oxo-2â²-deoxyguanosine pairs which enable to control G-quadruplex topologies. Thermodynamic analyses show that metal ions and cosolutes regulate G-quadruplex topologies through the sizes of metal ion cavities and hydration states.205
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Taiga Fujii, Peter Podbevšek, Janez Plavec, Naoki Sugimoto,