Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5153030 | Journal of Organometallic Chemistry | 2017 | 17 Pages |
Abstract
Ruthenium(II) arene compounds modified with bexarotene, a retinoid that selectively activates retinoid X receptors, prepared by tethering bexaroten to the ruthenium fragment via an imidazole linker. Docking studies show that the interactions of these compounds with possible targets are significantly different to the binding mode of the parent drug.239
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Yulia N. Nosova, Dmitry S. Karlov, Sergey A. Pisarev, Ilya A. Shutkov, Vladimir A. Palyulin, Mathurin Baquié, Elena R. Milaeva, Paul J. Dyson, Alexey A. Nazarov,