| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 51558 | Catalysis Communications | 2011 | 6 Pages |
Fe3O4–TiO2 core-shell nanocomposites were successfully prepared and characterized by FE-SEM, XRD, UV–vis absorbance spectra, and EDX. The FE-SEM and EDX studies revealed core-shell structure with a particle size of ca. 40–50 nm. We adopted HeLa cells as a model to investigate the thermal-photocatalytic cell killing efficiency of Fe3O4–TiO2 using 150 μg/mL dose content for 10 min exposure time. We found neither only AC magnetic-field induction nor only photoirradiation condition could kill the cancer cells up to satisfactory level using Fe3O4–TiO2 nanocomposites. Finally, the results revealed that almost 100% cancer cells were destructed by Fe3O4–TiO2 nanocomposites whereas for bare Fe3O4 and bare TiO2, 90% and 56% cancer cells were killed, respectively, under combined AC (alternating current) magnetic-field induction and UV–vis photoirradiated conditions.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Fe3O4–TiO2 core-shell nanocomposites were successfully prepared. ► We noticed the core-shell structure with a particle size of ca. 40–50 nm. ► Thermal-photocatalytic cancer cell killing efficiency was investigated. ► Combined AC magnetic-field induction and photoirradiation conditions were used. ► Significant enhanced cytotoxicity was found under combined conditions.
