Nanosize Co3O4 as a novel, robust, efficient and recyclable catalyst for A3-coupling reaction of propargylamines

Nanosize Co3O4 was prepared via hydrothermal synthesis and characterized using TEM, XRD, EDAX, XPS and BET surface area analysis. Prepared nanosize Co3O4 was found to be highly efficient catalyst for the synthesis of propargylamines via A3-coupling reaction. The catalyst was recycled up to ten consecutive cycles without any loss in its activity. The developed protocol offers efficient synthesis of diverse propargylamines eliminating the use of co-catalyst and activator as reported in earlier literature.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Nanosize Co3O4 acts as a heterogeneous and efficient catalyst for A3 reaction ► The catalyst is recyclable up to 10 recycles without significant loss in activity. ► Circumvents use of co-catalyst/activator. ► C–H bond activation. ► No inert atmosphere of Nitrogen/Argon was required.